Un 2ème appel à candidatures sera ouvert en janvier 2022
Our team is investigating cellular processes that identify and degrade faulty mRNAs and their corresponding aberrant peptides, potentially toxic to cells. Ribosome-based quality controls have received much attention during the past decade, leading to the characterization of highly conserved surveillance effectors that rescue stalled ribosomes and degrade aberrant/damaged mRNAs and truncated peptides. These studies have also revealed that alternative processes exist, involving mechanisms and factors of quality control that we aim to characterize using S. cerevisiae as a model organism.
More information/eligibility check.
http://labexdynamo.ibpc.fr/fp-dynamo-paris/
http://lbmce.ibpc.fr/fr/regulation-fonctionnelle-et-surveillance-de-larn/
contact : lionel DOT benard AT ibpc DOT fr